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This can lead to an imbalance in the redox potential, export of GSSG and eventual depletion of GSH, a classical state of oxidative stress [26] observed in a number of diseases including inflammation [27], autoimmune disorders [28,29] and liver disorders [30]

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3 Background Anatomy of the Biliary System The gallbladder is a pear-shaped, muscular, pouch-like organ that is roughly three to six inches long and sits under the liver in the upper right region of the abdomen